Deep sleep homeostatic response to naturalistic sleep loss.

ABSTRACT: Investigations of Deep sleep homeostasis, the process by which the amount of Deep sleep is increased following a night of reduced sleep, often involve controlled intentional sleep deprivation experiments in service of understanding mechanistic physiology. We tested the hypothesis that a homeostatic increase in Deep sleep is detectable after relative sleep loss arising in naturalistic settings. In this retrospective observational study, we analyzed participants who provided informed consent to participate in the Apple Heart and Movement Study and elected to contribute sleep data (n = 44,564). Instances of relative sleep loss, defined as >=2 hours below each participant's median duration, occurred in 92.9% of participants, most often in isolation, and with a median duration of just over 4 ho

SUBMITTER: Goparaju B 

PROVIDER: S-EPMC12500159 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature