Impact of post-admission changes in potentially inappropriate medication use on risk of subsequent hospitalization among nursing home residents.

ABSTRACT:

Objectives

As the population of nursing home (NH) residents grows, the management of polypharmacy and potentially inappropriate medications (PIMs) becomes crucial. Limited research exists on how changes in PIM use affect adverse outcomes, or the benefits of reducing such medications. This study explores post-admission trajectory of PIM utilization and polypharmacy, and their association with hospitalization risk.

Methods

Analyzing national claims data from 23,982 seniors aged ≥65 admitted to NHs from 2008 to 2018, we assessed PIM utilization based on the 2019 Beers criteria and calculated the total number of medications prescribed during the first month of each quarter in the year following NH admission. We then used a cause-specific hazard model to explore how changes in th

SUBMITTER: Zhao J 

PROVIDER: S-EPMC12500243 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature