Association Between Metabolic Syndrome and Incident Cervical Cancer: A Retrospective Cohort Study.

ABSTRACT:

Objective

To determine whether metabolic syndrome is associated with an elevated risk of cervical cancer.

Methods

We retrospectively analyzed data on 1,410,650 women without a history of cancer, using the JMDC Claims Database, a nationwide epidemiological database in Japan, between 2005 and 2022. The look-back period was set at 2 years. Cox regression analyses were conducted to assess cervical cancer risk associated with metabolic syndrome and its components (waist circumference, blood pressure, triglycerides, high-density lipoprotein cholesterol, and fasting plasma glucose). Further, we conducted age-stratified analyses.

Results

Metabolic syndrome was diagnosed in 43,029 participants (median age: 53 years), and 1579 cervical cancer cases were recorded over a median f

SUBMITTER: Jiang L 

PROVIDER: S-EPMC12500346 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature