Predictive value of systemic immune-inflammation index in patients with diabetes mellitus: a systematic review and meta-analysis.

ABSTRACT:

Background

Emerging evidence suggests an association between the systemic immune-inflammation index (SII) and the prognostic outcomes in individuals diagnosed with diabetes mellitus (DM). However, existing research presents inconsistent findings.

Methods

PubMed, Embase, Web of Science, and the Cochrane Library from their inception to December 9, 2024, were retrieved to identify studies that scrutinized the interaction between SII and prognostic outcomes in DM patients. Primary outcomes included diabetic nephropathy (DN), diabetic retinopathy (DR), all-cause mortality, cardiovascular mortality, peripheral artery disease(PAD), and kidney mortality. Data were analyzed using odds ratios (ORs) or standardized mean differences (SMDs) with 95% confidence intervals (CIs). To ensure

SUBMITTER: Dong Y 

PROVIDER: S-EPMC12500460 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature