Efficacy and safety of thoracic radiotherapy combined with anti-angiogenic therapy and immunochemotherapy for advanced non-small cell lung cancer patients: a retrospective study.

ABSTRACT:

Purpose

To assess the efficacy and safety of radiotherapy combined with anti-angiogenic therapy, immune checkpoint inhibitors, and chemotherapy for advanced non-small cell lung cancer (NSCLC).

Methods

Patients who have received at least two cycles of quadruple therapy were Progression-free survival (PFS), overall survival (OS), and treatment-related side effects were comprehensively evaluated using R language and the chi-square test.

Results

Seventy-four patients were enrolled and divided into two groups (A and B) based on whether they had received radiotherapy. The incidence rate of adverse events-such as radiation-related pneumonitis, pneumonia, thrombocytopenia, cough, panting, fatigue, and radiodermatitis-were significantly higher in patients receiving radiotherap

SUBMITTER: Gai K 

PROVIDER: S-EPMC12500576 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature