Systolic pulmonary artery pressure threshold to define pulmonary and peripheral congestion in acute heart failure in absence of severe tricuspid regurgitation.

ABSTRACT:

Background and aims

Pulmonary and/or peripheral venous congestion defines the clinical diagnosis of acute heart failure (AHF). However, the systolic pulmonary arterial pressure (sPAP) thresholds at which pulmonary (chest x-ray) and inferior vena cava (IVC) congestion occur are not well established. This study aimed to identify a cut-off value of sPAP that reliably indicates AHF.

Methods and results

We retrospectively included 380 consecutive patients hospitalized for AHF at an Italian referral centre, after excluding those with severe tricuspid regurgitation. Receiver operating characteristic (ROC) curve analysis and Youden's J statistic identified a threshold of sPAP ≥ 48.75 mmHg as the most accurate in predicting both pulmonary (sensitivity = 89.9%, specificity = 73%) and

SUBMITTER: Bellicini MG 

PROVIDER: S-EPMC12500580 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature