Neuronal effects of epicranial current stimulation in macaque cortex.

ABSTRACT:

Background

Transcranial electrical stimulation (TES) using scalp electrodes is noninvasive, safe and inexpensive. However, because the scalp shunts most of the current, electric fields (E-fields) in the brain are relatively weak. Conversely, invasive neuromodulation methods such as deep brain stimulation (DBS) and invasive cortical stimulation (ICS) successfully treat many brain diseases. However, the expensive and risky surgery limits the reach of these approaches. Epicranial current stimulation (ECS), where electrodes are implanted on the skull, is a novel approach which can bridge the gap between these two extremes. In current study we investigated the effects of ECS on neural activity.

Methods

In two macaque monkeys we implanted two concentric ring electrodes directly on

SUBMITTER: Asamoah B 

PROVIDER: S-EPMC12500610 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature