Changes in central and peripheral hemodynamic parameters during blood donation.

ABSTRACT:

Background

Blood donation is a common procedure, yet its acute effects on central and peripheral hemodynamics are not fully understood. This study aimed to systematically quantify immediate cardiovascular changes induced by whole blood donation in healthy adults, with a primary focus on arterial pressure and central hemodynamic parameters.

Methods

Thirty healthy volunteers (12 female, 18 male; median age 34 years, IQR 24-53) underwent standardized whole blood donation. Non-invasive measurements of central and peripheral hemodynamics were performed immediately before and after donation using the VascAssist 2 device, enabling assessment of brachial and aortic blood pressures, heart rate, augmentation index (AIx), pulse wave velocity (PWV), and left ventricular ejection time (L

SUBMITTER: Yazdani B 

PROVIDER: S-EPMC12500645 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature