Correlation analysis of osteoporosis and vertebral endplate defects using CT and MRI imaging: a retrospective cross-sectional study.

ABSTRACT:

Background

Osteoporosis (OP) and vertebral endplate defects are important manifestations of vertebral degenerative changes that greatly affect the quality of life of elderly people. This study investigated the potential association between vertebral endplate defects and osteoporosis using imaging modalities.

Methods

Computed tomography (CT), magnetic resonance imaging (MRI), bone mineral density (BMD) and other relevant imaging data, as well as age, sex, body mass index (BMI), and degree of low back pain data, were retrospectively analysed. The vertebral Hounsfield unit (HU) value and the maximum width and maximum depth of the vertebral endplate defect were measured and standardized. A HU <110 was defined as OP. Logistic regression was used to identify the risk factors for v

SUBMITTER: Hao S 

PROVIDER: S-EPMC12500679 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature