Saireito (TJ-114) for Preventing High-Output Syndrome After Temporary Ileostomy in Rectal Cancer Surgery.

ABSTRACT:

Purpose

In rectal cancer surgery, a temporary ileostomy is often created to prevent clinical anastomotic leakage. However, high-output syndrome (HOS) frequently arises as a postoperative complication. We aimed to investigate the preventive effect of Saireito, a traditional Japanese herbal medicine, on HOS in patients with a temporary ileostomy.

Methods

At the University of Osaka Hospital, Saireito has been routinely administered to patients undergoing rectal cancer surgery with a temporary ileostomy since October 2022. Patients received 9 g/day of Saireito in three divided doses starting from the afternoon of postoperative day 1 (POD1). Among 68 consecutive patients, five were excluded due to incomplete administration of Saireito according to the planned postoperative schedu

SUBMITTER: Uemura M 

PROVIDER: S-EPMC12500839 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature