Systematic review and meta-analysis of rural-urban disparities in Alzheimer's disease dementia prevalence.

ABSTRACT:

Background

The prevalence of Alzheimer's disease (AD) dementia varies between rural and urban areas worldwide, with studies reporting mixed patterns. In this study, we conducted a systematic review and meta-analysis to pool the odds ratio (OR) of rural-to-urban prevalence and explored contributing regional and socioeconomic factors.

Methods

We performed comprehensive searches in PubMed, MEDLINE, CINAHL, Web of Science, and Scopus (January 2000-August 2024) for peer-reviewed studies reporting individual-level AD dementia prevalence comparisons between rural and urban settings. A random-effects model was used to calculate pooled OR at a 95 % confidence interval (CI). Prespecified subgroup analyses examined variations by WHO-defined regions, healthcare expenditure, income level

SUBMITTER: Mollalo A 

PROVIDER: S-EPMC12501328 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature