Characterizing financial toxicity among people living with neuromyelitis optica spectrum disorder.

ABSTRACT:

Background

Financial toxicity (FT) and the social determinants of health (SDOH) remain underexplored in neuromyelitis optica spectrum disorder (NMOSD).

Objective

To characterize FT in NMOSD and examine sociodemographic and clinical features.

Methods

We conducted a convenience-sampled, cross-sectional, anonymous survey (08/2024-03/2025) of 124 U.S. adults. The COmprehensive Score for financial Toxicity (COST) was used to measure FT (lower COST = higher FT).

Results

Seventy-five percent had a COST < 25 points, consistent with FT. In multivariable analysis, a higher attack frequency was associated with a 1.20-point lower COST score (95% confidence interval [CI] -1.90, -0.50), and each one-unit increase in disability, as measured by the Patient-Determined Disease S

SUBMITTER: Hill JB 

PROVIDER: S-EPMC12501395 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature