Time-resolved mapping of myocardial stiffness using 2D multifrequency spiral MR elastography with and without external vibration.

ABSTRACT:

Purpose

There is a clinical need for stiffness mapping of the heart; however, current cardiac magnetic resonance elastography (cMRE) has limited spatiotemporal resolution. Therefore, we developed 2D spiral multifrequency MRE of the human heart and conducted a study to analyze the consistency and reproducibility of motion-encoding and stiffness mapping with and without external vibration.

Methods

Eleven healthy volunteers were studied using single-slice gradient-echo spiral cMRE with cardiac triggering and encoding of harmonic shear wave fields at 70, 80, and 90 Hz frequency generated by either external drivers or endogenous heart motion. Tissue displacement was monitored synchronized to the cardiac cycle, and frequency-resolved shear wave speed (SWS) maps were reconstructed

SUBMITTER: Anders MS 

PROVIDER: S-EPMC12501707 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature