Force-Induced Ring Flipping in a Threaded Pillar[5]Arene.

ABSTRACT: Pillar[n]arenes are popular macrocycles used in various supramolecular systems and materials due to their unique host-guest properties and ease of synthesis. Their pillar shape originates from the cyclic arrangement of methylene-bridged hydroquinone groups. They usually exist in one of two conformations where all the hydroquinone rings are oriented in the same direction (left or right), which is the source of their planar chirality. However, the controlled formation of pillar[n]arenes with intermediate conformations, for example, where only one ring is inverted, remains a challenge. Here we show how mechanical force can be used to reach this elusive conformation via the force-induced flipping of a single hydroquinone ring in a pillar[5]arene-based rotaxane. We show that the flipping motion

SUBMITTER: Chen L 

PROVIDER: S-EPMC12501734 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature