Treatment of Biopsy-Proven Laryngeal Squamous Cell Carcinoma In Situ.

ABSTRACT:

Objective

To investigate the impact of clinical surveillance, primary radiotherapy, and primary surgery on overall survival (OS) in laryngeal carcinoma in situ (Cis).

Methods

The 2006-2020 National Cancer Database was queried for adults with a biopsy-proven diagnosis of laryngeal Cis. Multivariable binary logistic and Cox proportional hazards regression models were implemented.

Results

Of 3567 unique patients satisfying inclusion criteria, 514 (14.4%) underwent clinical surveillance, 1074 (30.1%) underwent primary radiotherapy, and 1979 (55.5%) underwent primary surgery. Receiving treatment at an academic/research facility was associated with higher odds of undergoing primary surgery compared to primary radiotherapy. Among 646 patients undergoing primary surgery with

SUBMITTER: Kaki PC 

PROVIDER: S-EPMC12501767 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature