Impact of government-organized screening programs on the economic burden of cervical cancer across five disease courses: a multistage regression and mediation analysis.

ABSTRACT:

Objective

To evaluate the impact of government-organized screening on the economic burden among patients with cervical cancer and precancerous lesions, and explore mediating pathways across diagnosis, initial treatment, radiotherapy/chemotherapy, follow-up, and recurrence/progression/metastasis.

Methods

A multicentre, nationwide survey across 5 disease courses was conducted from 26 hospitals in China. Multivariable regression and structural equation modeling were used to assess the effects of government-organized screening on economic burden by comparing government-organized screening with workplace check-up, self-paid check-up, and symptom-based detection.

Results

Workplace check-up, self-paid check-up, and symptom-based detection were associated with progressively h

SUBMITTER: Dong M 

PROVIDER: S-EPMC12501897 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature