Characteristics of "Very Early" Intrahepatic Cholangiocarcinoma Undergoing Liver Resection and Its Relationship With Carbohydrate Antigen 19-9.

ABSTRACT:

Introduction

The concept of "very early" ICC ( ≤ 2 cm, single tumor) has been introduced in the context of LT. Due to the limited number of patients in this subset, the characteristics and long-term outcomes have been ill-defined. We sought to assess long-term outcomes of very early ICC patients undergoing liver resection using a large, multi-institutional database.

Methods

Patients who underwent curative-intent hepatectomy for ICC between 1993 and 2023 were identified from the International Intrahepatic Cholangiocarcinoma Study Group database. Multivariable Cox regression analysis was performed to identify the risk factors related to overall survival (OS) and recurrence-free survival (RFS).

Results

Among 1868 ICC patients, 86 (4.6%) met the criteria for very early IC

SUBMITTER: Endo Y 

PROVIDER: S-EPMC12501924 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature