Drug-Coated Balloon-Based Versus Drug-Eluting Stent-Only Treatment for Large Vessel Coronary Artery Disease.

ABSTRACT:

Background

Drug-coated balloon (DCB) treatment has shown outcomes comparable to drug-eluting stent (DES) in small vessel coronary disease. However, evidence for its application in large vessel coronary artery disease (CAD) remains limited.

Aims

This study evaluated the clinical impact of DCB-based percutaneous coronary intervention (PCI) in patients with large vessel CAD.

Methods

We retrospectively enrolled 550 consecutive patients with reference vessel diameter ≥ 3.0 mm treated with DCB-based PCI and propensity-matched them 1:1 to 550 patients who underwent conventional PCI with second-generation DES (DES-only group). The primary endpoint was 2-year major adverse cardiac events (MACE), defined as a composite of cardiac death, non-fatal myocardial infarction, definite

SUBMITTER: Shin ES 

PROVIDER: S-EPMC12502026 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature