Minimum Lumen Area Indexed to Left Ventricular Mass to Identify Functionally Significant Left Main Coronary Stenoses.

ABSTRACT:

Background and aim

Diagnosing significant left main coronary artery (LMCA) stenoses based on anatomical criteria remains challenging. The ARMYDA FINISH multicenter study evaluated whether indexing intravascular ultrasound (IVUS)-derived minimum lumen area (MLA) provides greater diagnostic accuracy than unindexed MLA for detecting hemodynamically significant LMCA stenoses, defined as a fractional flow reserve (FFR) ≤ 0.80.

Methods

Fifty-two patients with angiographically-intermediate isolated LMCA lesion were prospectively enrolled. All patients underwent IVUS and FFR measurements. Primary endpoint was the diagnostic accuracy of MLA indexed to height, body surface area (BSA), body mass index (BMI) and left ventricular (LV) echocardiographic mass in identifying hemodynamically

SUBMITTER: Patti G 

PROVIDER: S-EPMC12502031 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature