Re-Exploration of Flow Rate in Low-Flow, Low-Gradient Aortic Stenosis.

ABSTRACT:

Background

Transaortic flow rate (TFR, mL/s) is an emerging hemodynamic index in aortic stenosis (AS), offering insights beyond stroke volume index (SVi). We evaluated the hemodynamic determinants and prognostic significance of TFR at rest and peak dobutamine stress in patients with suspected low-flow, low-gradient (LF-LG) AS and reduced left ventricular ejection fraction (LVEF < 50%).

Aims

This study aimed to assess and compare the hemodynamic determinants of TFR at rest and during peak pharmacological stress, and to evaluate their association with 3-year survival.

Methods

Among 86 patients undergoing dobutamine stress echocardiography (DSE), 34 were classified as true severe, eight as pseudo-severe, and 44 as indeterminate AS. TFR and associated parameters were asse

SUBMITTER: Hungerford S 

PROVIDER: S-EPMC12502037 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature