Choosing sweeteners wisely-nutrigenetic study on childhood obesity.

ABSTRACT:

Background

This study investigated the association of specific sweet-taste and obesity-related genes with sweetener consumption patterns among children and the interaction between these genetic factors and sweetener intake on the risk of childhood obesity. By leveraging data from the Taiwanese Pubertal Longitudinal Study (TPLS), the current study minimized the influence of environmental confounders commonly encountered in adult studies, offering a more precise understanding of these relationships in pediatric and adolescent populations.

Methods

Participants in the TPLS underwent genetic sampling, anthropometric measurements, puberty stage assessments, dietary recall, and measurements of relevant lifestyle variables. Nonnutritive sweetener (NNS) intake was assessed using the

SUBMITTER: Qiu DW 

PROVIDER: S-EPMC12502141 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature