High sodium intake: a silent killer driving global gastric cancer burden.

ABSTRACT:

Background

High sodium intake is a recognized risk factor for increased gastric cancer mortality. This study examines the trends and distribution of stomach cancer burden associated with high sodium intake from 1990 to 2021, with a focus on its relationship with age, period, and birth cohort.

Methods

Utilizing data from the 2021 Global Burden of Disease study, we applied an age-period-cohort model to conduct statistical analysis. We calculated age, period, and cohort effects, as well as net drift (overall annual percentage change), for gastric cancer deaths and disability-adjusted life years (DALYs) associated with high sodium intake across 204 countries and regions.

Results

In 2021, 7.93% of global gastric cancer deaths and 7.92% of DALYs were linked to high sodium i

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12502230 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature