Integrated metabolomic and transcriptomic profiling reveals leaf-specific flavonoid biosynthesis in Paris polyphylla Sm.

ABSTRACT: BACKGROUND : Paris polyphylla Sm. is a precious medicinal plant rich in various active ingredients. In addition to the well-known saponins, the flavonoids it contains have unique pharmacological potential in antioxidant, neuroprotective, and metabolic regulation. However, the flavonoids in Paris polyphylla Sm. have not been fully researched and developed yet. In this work, we conducted a comprehensive metabolomics and transcriptomics analysis to reveal the metabolic differences and biosynthetic mechanisms of flavonoids in the leaves, stems, and roots of Paris polyphylla Sm. RESULTS: Non-targeted metabolomics analysis detected a total of 332 metabolites in Paris polyphylla Sm., among which flavonoids accounted for 19.49%. The diversity and abundance of flavonoids in leaves are the highest,

SUBMITTER: Yang W 

PROVIDER: S-EPMC12502438 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature