Analysis of <i>Neisseria gonorrhoeae</i> and <i>Mycoplasma genitalium</i> from nucleic acid amplification test specimens, Nunavut region of Inuit Nunangat, Canada, 2020-2023.

ABSTRACT: This study analyzed Neisseria gonorrhoeae (GC) and Mycoplasma genitalium (Mgen) from remnant nucleic acid amplification test (NAAT) specimens in Nunavut, Canada (2020-2023) to assess strain distribution, antimicrobial resistance (AMR), and co-infection rates. Among 2,221 GC-positive specimens, no cephalosporin resistance was detected, but intermediate-to-decreased susceptibility increased in 2023. Predicted ciprofloxacin resistance was 45%, and azithromycin resistance remained stable at 9.6%. Of 778 tested specimens, 31.4% were co-infected with Mgen, with 49.2% associated with azithromycin resistance, but none with moxifloxacin resistance. These findings highlight emerging AMR trends and support reassessment of current treatment guidelines. Remnant urine specimens submitted f

SUBMITTER: Barairo N 

PROVIDER: S-EPMC12502515 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature