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Analysis of clinicopathological features and clinical significance in 25 cases of mammary adenoid cystic carcinoma.


ABSTRACT:

Background

Mammary adenoid cystic carcinoma (AdCC) is a rare subtype of invasive breast cancer. Due to its low incidence, the clinicopathological features of mammary AdCC remain incompletely understood. This study aimed to investigate the clinicopathological and molecular characteristics, therapeutic regimens, and prognostic outcomes associated with different subtypes of mammary AdCC.

Methods

A total of 25 archived specimens of mammary AdCC were collected from the pathology departments of Nanchang People's Hospital and Zhengzhou People's Hospital between January 2013 and December 2024. Histomorphological evaluation, immunohistochemical (IHC) analysis, and molecular testing were performed to evaluate the clinicopathological features and prognostic outcomes. Fisher's exact tes

SUBMITTER: Xu X 

PROVIDER: S-EPMC12502641 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature