Emergence of carbapenem-resistant <i>Serratia marcescens</i> co-harboring <i>bla</i><sub>NDM-1</sub>, <i>bla</i><sub>KPC-2</sub>, and <i>bla</i><sub>SRT-2</sub> in bloodstream infection.
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ABSTRACT: Serratia marcescens is an emerging opportunistic pathogen with high genetic diversity. The emergence and prevalence of carbapenem-resistant S. marcescens poses a major health threat due to its intrinsic resistance to multiple antibiotics, which severely restricts the selection and treatment of antibiotics for S. marcescens infection. This study presents the first documented case in China of a bloodstream infection caused by Staphylococcus epidermidis and S. marcescens strain (designated S96) co-producing blaNDM-1, blaKPC-2, and blaSRT-2. Strain S96 exhibited resistance to nearly all categories of β-lactam antimicrobials, β-lactam/inhibitor combinations, aminoglycosides, quinolones, and other clinical a
SUBMITTER: Wang X
PROVIDER: S-EPMC12502704 | biostudies-literature | 2025 Oct
REPOSITORIES: biostudies-literature
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