H1N1pdm09 returns: a comparative study in Anhui, China.

ABSTRACT: The 2022/2023 season witnessed a rapid resurgence of H1N1pdm09 in Anhui Province, China, surpassing previous years, prompting an examination of hemagglutinin (HA) gene mutations and cross-immunity in this study. Anhui Province's surveillance data established the detection threshold for H1N1pdm09 using the Moving Epidemic Method. Joinpoint regression compared weekly percent change (WPC) rates. A total of 103 strains of H1N1pdm09 were sequenced and analyzed, and cross-reactivity was assessed using P_epitope model. The ILI% (percentage of outpatient visits for influenza-like illness) and influenza detection rate for the 2022/2023 season were 6.82% and 31.90%, respectively, which surpassed those of 2017/2018-2021/2022. The H1N1pdm09 subtype dominated this outbreak. The epidemi

SUBMITTER: Yang S-T 

PROVIDER: S-EPMC12502789 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature