Development of a multiplex serological assay to detect immunoreactivity against a novel <i>Bartonella species</i> in military working dogs.

ABSTRACT: Bartonella pose a significant health risk to military working dogs (MWDs), and these zoonotic organisms may also cause disease in humans. According to the U.S. Army zoonotic disease surveillance program, there was a 47.4% seroprevalence for Bartonella spp. among feral dogs in Iraq. This surveillance program identified infection with a novel species Candidatus Bartonella merieuxii (CBm) in 37% of the dogs by whole blood Bartonella DNA amplification and sequencing for the gltA and rpoB genes and intergenic spacer region. This bacterium has not been successfully cultured to date. The objectives of the present study were to (i) develop an assay to serologically detect infection with CBm in dogs, and (ii) to define the prevalence and Ba

SUBMITTER: de Araujo FF 

PROVIDER: S-EPMC12502796 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature