Model for small-angle scattering analysis of membranes with protein-like inclusions.

ABSTRACT: Proteins are ubiquitous in biological membranes and have a significant impact on their scattering properties. In this contribution, we introduce a general mathematical construction to add proteins to any pre-existing membrane model and to calculate the resulting elastic and/or inelastic scattering cross section. The model is a low-resolution one, which describes the proteins as made up of regions of homogeneous scattering length density that extend through an arbitrary fraction of the membrane and possibly protrude out of it. In this construction, the protein characteristics that are relevant to scattering are their space and time correlation functions in the two-dimensional plane of the membrane. The results are particularized to a static bilayer model and to a Gaussian model of a fluctua

SUBMITTER: Gommes CJ 

PROVIDER: S-EPMC12502873 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature