CandyCollect open-to-closed (O2C) microfluidic system for rapid and user-centric detection of group A <i>Streptococcus</i>.

ABSTRACT: We created CandyCollect, a lollipop-inspired, child-friendly saliva sampling device that provides enhanced comfort compared to common throat and mouth swabs. The device has an open microchannel and a functionalized surface that effectively captures and stores the saliva and pathogens. We recently demonstrated the ability to combine the CandyCollect with rapid antigen detection tests (RADTs) for fast and accessible detection of group A Streptococcus (GAS). However, the current procedure necessitates manual steps to elute and transfer captured antigens from the lollipop to RADTs, which relies on the user to follow complex instructions, increasing the likelihood of error. In this work, we developed the CandyCollect open-to-closed (O2C) microfluidic system to automate antigen elution an

SUBMITTER: Leong KM 

PROVIDER: S-EPMC12502896 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature