Comparison of computed tomography coronary angiography (CTCA) alone vs. CTCA with selective FFR_CT in patients presenting with stable chest pain: a FORECAST trial substudy.

ABSTRACT:

Aims

The original FORECAST trial was designed to compare a strategy of computed tomography coronary angiography (CTCA) and selective FFR_CT to standard care in patients attending Rapid Access Chest Pain clinics in UK centres. This is a prespecified analysis of the FORECAST trial to compare outcomes between the patients in the experimental arm (CTCA + selective FFR_CT) and patients in the reference arm who underwent CTCA alone as their initial test of choice.

Methods and results

The FORECAST trial recruited 1400 patients randomized between two strategies: (i) initial test of choice at the discretion of the healthcare provider (standard care arm) or (ii) CTCA ± FFR_CT. Prior to randomization, clinicians stated their preference for choice of the fi

SUBMITTER: Kira M 

PROVIDER: S-EPMC12502911 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature