Long-Term Outcomes of BK Viremia in Kidney Transplant Recipients.

ABSTRACT:

Background

BK viremia is associated with worse kidney transplant function and de novo donor-specific antibodies (DSA), but mortality and graft survival are not impacted in the short- and intermediate-term. The long-term impact of BK viremia remains unclear.

Methods

We performed a single-center retrospective study on 1058 consecutive kidney or kidney-pancreas transplant recipients. We classified the cohort based on the presence or absence of BK viremia, BK viral loads, persistence of BK viremia, and pre-existing or de novo DSA. Outcomes included mortality, graft loss, death-censored graft survival (DCGS), estimated glomerular filtration rate, biopsy-proven acute rejection (BPAR), de novo DSA, ureteral stenosis, and genitourinary (GU) malignancies.

Results

Over a median

SUBMITTER: Tandukar S 

PROVIDER: S-EPMC12503080 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature