Publication Bias in Randomized Controlled Trials of Hypospadias Surgical Repair: A Systematic Review.

ABSTRACT:

Objectives

Hypospadias is a common congenital condition in males that has been subject to extensive research. However, publication bias can distort the scientific literature and impact clinical decision-making. This review evaluates publication bias in hypospadias research and emphasizes the need for balanced reporting to improve clinical practices and enhance patient care.

Methods

A literature search was conducted using four public databases to identify peer-reviewed randomized controlled trials (RCT) of surgical interventions for hypospadias. The primary outcomes were success rate and complication rate. We assessed the publications using the Risk of Bias 2 (RoB-2) tool and evaluated the quality of evidence using the GRADE method. Data were collated and recalculated using R

SUBMITTER: Nainggolan E 

PROVIDER: S-EPMC12503199 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature