Antibacterial activity and genomic characterisation of a novel <i>Brevibacillus laterosporus</i> XJ-24-3 isolated from Xinjiang, China.

ABSTRACT:

Introduction

Brevibacillus laterosporus is a significant probiotic with notable antimicrobial activity. This study employs a genome-guided discovery strategy to elucidate the molecular mechanisms and antimicrobial potential of a novel B. laterosporus isolate against multidrug-resistant pathogens.

Material and methods

A B. laterosporus strain designated XJ-24-3 was isolated from the soil of a pasture area in Xinjiang, China using the dilution plate method. The XJ-24-3 isolate was identified and characterised by morphology, biochemical properties and 16S rRNA gene sequencing.

Results

The bacterium exhibited bactericidal activity against diverse foodborne pathogens, including methicillin-resistant Staphylococcus aureus. Functional genome annot

SUBMITTER: Wu M 

PROVIDER: S-EPMC12503217 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature