Advance care planning in multiple sclerosis (ConCure-SM): A multicenter single-arm pilot and feasibility study.

ABSTRACT:

Background

Advance care planning (ACP) practice in people with progressive multiple sclerosis (PwPMS) remains limited. ConCure-SM project aims to assess the effectiveness of a structured ACP intervention (clinician's training programme and use of a booklet during ACP conversations) using a multi-phased design.

Methods

Single-arm pilot/feasibility trial involving PwPMS, their significant others (SOs), and clinicians from six Italian centers. Primary study outcome was completion of an advance care plan document (ACP-Doc). Other outcomes included safety, feasibility of enrollment and assessment, and (analyzed using mixed-methods approach) Hospital Anxiety and Depression Scale (HADS), quality of communication, quality of life (MSQOL-29), and caregiver burden. Participants were i

SUBMITTER: Solari A 

PROVIDER: S-EPMC12503263 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature