Can lipid indices aid in predicting diabetic kidney disease? Findings from a cross-sectional, matched case-control study.

ABSTRACT:

Background

This study explored the association between lipid indices, including AC, TG/HDL-C ratio, AIP, and LCI, and diabetic kidney disease (DKD).

Methods

A cross-sectional, matched case-control study was conducted involving patients with type 2 diabetes (T2D), divided into two groups based on the presence of DKD. The groups were matched for age and duration of diabetes. The association between lipid indices and DKD was assessed using RCS, multivariable logistic regression, and ROC curve analysis.

Results

The study included 2940 individuals with T2D, with 1470 in each group. A nonlinear association was observed between all lipid indices and the presence of DKD. These lipid indices demonstrated relatively high predictive ability for DKD, with all AUC values higher th

SUBMITTER: Yadegar A 

PROVIDER: S-EPMC12503270 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature