Global burden of polycystic ovary syndrome in women of reproductive age, 1990-2021: Analysis of the global burden of disease study 2021 with projections to 2050.

ABSTRACT:

Objective

To evaluate the global burden of polycystic ovary syndrome (PCOS) among women of reproductive age from 1990 to 2021.

Methods

This study analyzed population-based data from the Global Burden of Disease (GBD) database on the incidence, prevalence, and disability-adjusted life years (DALYs) of PCOS in reproductive-aged women. Age-standardized rates for incidence (ASIR), prevalence (ASPR), and DALYs (ASDR) were calculated per 100,000 population, with 95% uncertainty intervals (UIs). Data from 204 countries and territories were stratified by age, location, and socio-demographic index (SDI).

Results

Globally, the burden of PCOS among reproductive-aged women in 2021 was characterized by ASIR of 64.44 (95% UI: 39.07, 103.40) per 100,000 population, ASPR of 3364.53 (

SUBMITTER: Zheng X 

PROVIDER: S-EPMC12503323 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature