Regional Practice Variation in the Management of Renal Replacement Therapy Modalities in the STARRT-AKI Trial.

ABSTRACT:

Introduction: The assess whether, in high-income countries, in the STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial, the management of the chosen initial renal replacement therapy modality varied by region and whether such variation was associated with different outcomes.

Methods

Post hoc analysis of the STARRT-AKI trial, including 142 ICUs in 13 countries. We evaluated 1,395 patients with severe AKI from North America, Europe, and Australia-New Zealand (ANZ) who received continuous renal replacement therapy (CRRT) as a first modality and 684 patients from North America and Europe who received intermittent hemodialysis (IHD) as a first modality.

Results

Among CRRT-first patients, femoral vascular access (p < 0.001)

SUBMITTER: Serpa Neto A 

PROVIDER: S-EPMC12503440 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature