Low Hand Grip Strength Is Associated with Increased Risk of Cognitive Impairment in Older Men, Including Men with Probable Sarcopenic Obesity: Results from the Northern Ireland PRIME-COG Cohort.

ABSTRACT:

Introduction: The relationship between cognitive impairment and a phenotype comprising low muscle strength coupled with excess adiposity, representative of sarcopenic obesity, is not well defined. The present study aimed to elucidate the relationship between low hand grip strength (HGS), representative of "probable sarcopenia," coupled with obesity, thus representing "probable sarcopenic obesity" and cognitive impairment.

Methods

Logistic regression models were implemented between probable sarcopenia and cognitive impairment in older men residing in Northern Ireland within the Prospective Epidemiological Study of Myocardial Infarction (PRIME)-COG cohort, a nested study in the PRIME cohort. In addition, associations across BMI strata were evaluated, including probable sarcopenic o

SUBMITTER: Farsi DN 

PROVIDER: S-EPMC12503445 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature