Reactive Intravascular Plasmablastic/Immunoblastic Proliferation in a Patient with Concurrent Gastric Mucosa-Associated Lymphoid Tissue Lymphoma and Tuberculosis Potentially Mimicking Aggressive Intravascular Lymphoma: A Rare Case Report.

ABSTRACT:

Introduction

Reactive intravascular plasmablastic/immunoblastic proliferation (RIVPIP) is rarely reported. RIVPIP may histologically mimic aggressive intravascular lymphoma, especially in the context of an old patient presenting with concurrent indolent lymphoma and tuberculosis, and easily lead to erroneous diagnosis.

Case presentation

A 79-year-old female presenting with upper abdominal discomfort, weight loss, hypoproteinemia, and polyserosal effusions underwent a gastric endoscopy examination. Biopsy revealed that the lamina propria was infiltrated by a large number of uniformly small-sized lymphocytes (CD20+/PAX5+) with lymphoepithelial lesions and epithelioid granuloma. Notably, vascular lumens were filled and distended by abundant large-sized plasmablasts or immunobla

SUBMITTER: Zhong LL 

PROVIDER: S-EPMC12503462 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature