Rare Extraskeletal Ewing Sarcoma of the Anterior Abdominal Wall: A Diagnostic Challenge.

ABSTRACT:

Introduction

Ewing sarcoma (ES) is a highly malignant neoplasm, typically arising from bone in children and young adults. Extraskeletal Ewing sarcoma (EES), involving soft tissues without bone involvement, represents a small fraction of ES cases. Even rarer is its manifestation in the anterior abdominal wall.

Case presentation

We report a case of a 27-year-old male presenting with right iliac fossa pain and a palpable mass, ultimately diagnosed as EES of the anterior abdominal wall. Radiological imaging revealed a soft tissue tumour within the rectus sheath with evidence of pulmonary metastasis. Histopathological analysis revealed small round blue cells, and immunohistochemistry demonstrated strong positivity for CD99, FLI1, WT1, and synaptophysin, confirming the diagnosis.

SUBMITTER: Raj S 

PROVIDER: S-EPMC12503465 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature