Disseminated Histoplasmosis as a Cause of a Small Bowel Mass and Cholestatic Liver Injury in an Immunocompetent Host: A Case Report.

ABSTRACT:

Introduction

Disseminated histoplasmosis is a rare cause of granulomatous, cholestatic liver disease. It can also manifest with gastrointestinal (GI) tract involvement, usually with ulceration or mucosal thickening, but is rarely reported as a cause of mass lesions in the GI tract. It is also very rare for disseminated histoplasmosis to present in an immunocompetent host.

Case presentation

We present a case of cholestatic liver disease and a small bowel mass in a 50-year-old male that has not previously been described in an immunocompetent host.

Conclusion

Timely diagnosis requires a high index of suspicion, particularly if there has been exposure to high-risk environments such as contaminated soils, as delayed diagnosis is associated with significant mortality.

SUBMITTER: Kerkham AL 

PROVIDER: S-EPMC12503467 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature