Association of Heart Rate Variability with Postnatal Maturation in Preterm Infants.

ABSTRACT:

Introduction: We assessed whether longitudinal measurements of sample entropy (SampEn) of heart rate time series reflect postnatal maturation in preterm infants and evaluated its predictive value at 32 weeks of postmenstrual age (PMA) for estimating discharge home. We further compared SampEn of preterm infants at discharge with that of term infants.

Methods

We conducted a prospective study at the University Children's Hospital Basel, Switzerland, from 2018 to 2022. We included preterm infants born before 32 weeks of gestation and a control group of term infants. Heart rate was recorded using the clinical monitoring system. We assessed preterm infants at 32 and 36 weeks of PMA, and at discharge, term infants were evaluated between 3 and 28 days of life. SampEn was calculated from

SUBMITTER: Kaempfen S 

PROVIDER: S-EPMC12503498 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature