Reirradiation for Sinonasal Adenoid Cystic Carcinoma in a Low-Middle Income Setting: A Case Report and Literature Review.

ABSTRACT:

Introduction

Reirradiation for recurrent adenoid cystic carcinoma (ACC) of the head and neck poses significant clinical challenges, particularly in low- and middle-income countries where access to advanced radiation modalities such as proton or carbon ion therapy is limited. Given the tumor's radioresistant nature and the risk of cumulative toxicity to critical structures, reporting experiences with accessible and precise photon-based techniques remains essential. This case highlights the potential of volumetric-modulated arc therapy (VMAT) as a feasible reirradiation option in such settings.

Case presentation

We report the case of a 79-year-old male with a history of left ethmoidal sinus ACC initially treated with surgery followed by cobalt-based radiotherapy. Eighteen year

SUBMITTER: Kaabia W 

PROVIDER: S-EPMC12503556 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature