Oral Isotretinoin for Facial Discoid Dermatosis: Effectiveness, Safety, and Clinical Suitability - Case Report of Complete Response and Literature Review.

ABSTRACT:

Introduction

Facial discoid dermatosis (FDD) is a rare dermatological condition, first described in 2010. Its aetiology remains unknown and it is distinguished by its resistance to several treatments, both topical and systemic. The lack of documentation in the medical literature makes this disease a significant diagnostic and therapeutic challenge.

Case presentation

A 51-year-old woman consulted for the appearance of pruritic skin lesions on the face, neck and upper chest of 2 months' duration. She underwent various topical and systemic therapies without complete resolution over a period of 9 months. Histological examination revealed psoriasiform irregular epidermal hyperplasia, mild spongiosis, parakeratosis, and hypogranulosis. In the superficial dermis, perivascular lymph

SUBMITTER: Rodriguez-Troncoso M 

PROVIDER: S-EPMC12503557 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature