Histologic Clearance of a Giant Cutaneous Squamous Cell Carcinoma with Imiquimod 5% Cream: A Case Report.

ABSTRACT:

Introduction

Cutaneous squamous cell carcinoma (cSCC) is one of the most common skin cancers, with an increasing incidence worldwide. Chronic sun exposure is a major risk factor and lesions are usually observed on sun-exposed areas such as the face, neck, scalp, and hands. Imiquimod cream, an immune response modifier, has shown promising results in the management of selected cases of cSCC.

Case report

A 70-year-old, Filipino male presented with 3-year history of a slow growing erythematous plaque on the abdomen. Physical examination revealed a solitary, well-defined, erythematous plaque measuring 5 cm on the left lower quadrant of the abdomen. Histopathologic examination confirmed cSCC. The patient declined surgery and opted for topical treatment with imiquimod 5% cream, app

SUBMITTER: Nazal MEBH 

PROVIDER: S-EPMC12503607 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature