Nephritis-Associated Plasmin Receptor-Positive Post-Streptococcal Acute Glomerulonephritis Showing Full-House Pattern: A Case Report.

ABSTRACT:

Introduction

Post-streptococcal acute glomerulonephritis (PSAGN) is a disease in which patients develop hematuria and leg edema following streptococcal infection, which may lead to acute nephritic syndrome and nephrotic syndrome. We present a case involving acute kidney injury and nephrotic syndrome with nonspecific pathological findings for PSAGN, which posed diagnostic challenges.

Case presentation

A 25-year-old man presented with leg edema, cough, nephrotic syndrome, severe kidney dysfunction, and hematuria. Blood tests showed elevated antistreptolysin O levels and decreased complement C3 levels; therefore, PSAGN was suspected. Light microscopy revealed membranoproliferative glomerulonephritis, immunofluorescence staining revealed a full-house pattern, and electron micros

SUBMITTER: Takahashi Y 

PROVIDER: S-EPMC12503611 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature