Prognostic Effect of Impaired Skeletal Muscle Assessed with Computed Tomography Images in Patients with Endoscopic Resection for Esophageal Squamous Cell Carcinoma.

ABSTRACT:

Introduction

No studies have investigated the prognostic effect of skeletal muscle mass and quality and adipose tissue distribution in patients who undergo endoscopic resection (ER) for esophageal squamous cell carcinoma (ESCC). Thus, this study aimed to evaluate their association.

Methods

We retrospectively collected data from patients who underwent ER for ESCC at our institution between 2005 and 2020. Multivariate Cox analysis was performed to investigate the association of 17 candidate factors, including indices for skeletal muscle mass and quality and adipose tissue distribution assessed with computed tomography (CT) images, with prognosis. Further, we evaluated the association of impaired skeletal muscle, characterized by the combination of low skeletal mass index (SMI)

SUBMITTER: Tanno N 

PROVIDER: S-EPMC12503655 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature