Curative Treatment after Immunotherapy Leads to Excellent Outcomes in Patients with Hepatocellular Carcinoma.

ABSTRACT:

Introduction

The high response rates observed with immunotherapy may allow downstaging to curative treatment in hepatocellular carcinoma (HCC). We aimed to investigate the factors associated with curative treatment receipt after immunotherapy and its outcomes.

Methods

HCC patients who received immunotherapy as a first-line treatment during 2017-2020 were identified from the US National Cancer Database. Patients were classified into two groups: immunotherapy with subsequent curative treatment (resection, transplantation, and local ablation) and immunotherapy without curative treatment. Multivariable Cox regression analysis was performed to determine factors associated with OS, followed by propensity score (PS) matching and inverse probability of treatment weighting (IPTW)-adj

SUBMITTER: Choi GH 

PROVIDER: S-EPMC12503716 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature