Assessment of Survival Benefits Derived from Surgical Resection Subsequent to the Attainment of Complete Response upon Triple Therapy in Hepatocellular Carcinoma: A Multicenter Study.

ABSTRACT:

Introduction

The necessity of surgical resection for hepatocellular carcinoma (HCC) patients who achieve clinical complete response (CR) following triple therapy (transarterial chemoembolization, targeted therapy, and immunotherapy) remains controversial. Thus, this study aimed to compare survival outcomes between surgical resection and nonsurgical management in these patients.

Methods

Between January 2018 and March 2024, 127 HCC patients who achieved clinical CR (cCR) following triple therapy were retrospectively included in this study. Patients were stratified into two groups based on whether they underwent surgical resection: the surgical resection group (n = 62) and the nonsurgical resection group (n = 65). Clinical characteristics, imaging findings, pathol

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12503757 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature